Construction of Cell-Resistant Surfaces by Immobilization of Poly(ethylene glycol) on Gold

Thumbnail Image
Supplemental Files
Date
2004-01-01
Authors
Mougin, K.
Lawrence, M.
Fernandez, E.
Hillier, Andrew
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Authors
Research Projects
Organizational Units
Journal Issue
Is Version Of
Versions
Series
Department
Chemical and Biological Engineering
Abstract

Considerable effort has been expended in efforts to create surfaces that resist the adsorption of proteins and cells for biomedical applications. The majority of such work has focused on surfaces constructed from bulk polymers or thin polymer films. However, the fabrication of surfaces via self-assembled monolayers (SAMs) has attracted considerable interest because of the robustness, versatility, and wide-ranging applicability of these materials. SAMs are particularly appealing for biological systems where well-defined surface chemistries can be created to facilitate coupling, biorecognition, or cell adhesion along with a host of other applications in biochemistry and biotechnology.

Comments

This article is from Langmuir 20 (2004): 4302-4305, doi: 10.1021/la049824a. Posted with permission.

Description
Keywords
Citation
DOI
Copyright
Thu Jan 01 00:00:00 UTC 2004
Collections