Real-time monitoring of pavement conditions is beneficial not only to more accurate predictions of airport pavement performance but also to more efficient pavement management activities. Although wireless-based sensing system have shown some advantages compared to wired sensing system, there are just few studies that describe instrumenting wireless sensors in the field for pavement condition monitoring. To bridge this gap, this paper presents case studies describing use of advanced wireless sensing system for airport pavement conditions monitoring at three test sites: the Des Moines International Airport (DSM), the Ohio State University (OSU) Airport, and the Texas A&M University (TAMU) Airport. The wireless sensors communicate through a gateway to collect sensor data and then upload it to the cloud. The wireless sensor instrumentation strategy and design plans, based on the field instrumentation experience, are summarized. The key requirements and potential restrictions for implementing wireless sensing systems in airfield pavement are also discussed.