A polyanhydride-based implantable single dose vaccine platform for long-term immunity
Date
2018-02-08
Authors
Mendoza, Kriscelle
Jackman, John
Narasimhan, Balaji
Jones, Douglas
Major Professor
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Jackman, John
Associate Professor
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Brewer, Matt
Associate Professor
Person
Narasimhan, Balaji
Distinguished Professor
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Organizational Unit
Veterinary Pathology
The Department of Veterinary Pathology Labs provides high quality diagnostic service to veterinarians in Iowa and throughout the Midwest. Packages may be delivered through the postage service or by dropping samples off at our lab in Iowa State University’s College of Veterinary Medicine campus.
Organizational Unit
Organizational Unit
Industrial and Manufacturing Systems Engineering
The Department of Industrial and Manufacturing Systems Engineering teaches the design, analysis, and improvement of the systems and processes in manufacturing, consulting, and service industries by application of the principles of engineering. The Department of General Engineering was formed in 1929. In 1956 its name changed to Department of Industrial Engineering. In 1989 its name changed to the Department of Industrial and Manufacturing Systems Engineering.
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Veterinary PathologyChemical and Biological EngineeringIndustrial and Manufacturing Systems EngineeringNanovaccine Institute
Abstract
Traditionally, immune priming followed by an antigen-boost is utilized for vaccine-induced protective immunity and maintaining long-term immunity often requires repeated exposure to antigen. Here, a novel single dose vaccination platform designed with gonadotropin releasing hormone multiple antigenic peptide as a model antigen is shown.
Comments
This article is published as Schaut, Robert G., Matthew T. Brewer, Kriscelle Mendoza, John Jackman, Balaji Narasimhan, and Douglas E. Jones. "A polyanhydride-based implantable single dose vaccine platform for long-term immunity." Vaccine 36, no. 7 (2018): 1024-1025. DOI: 10.1016/j.vaccine.2017.11.067.