We report the synthesis of hexagonal LaVxCr1−xGe3 (x=0–0.21, 1.00) single crystals and present a systematic study of this series by measurements of temperature- and field-dependent magnetic susceptibility, magnetization, resistivity, and specific heat. Ferromagnetism has been observed for x=0–0.21. The Curie temperature declines monotonically as the V concentration increases. Single-crystalline samples could only be grown for x values up to 0.21 for which the transition temperature was suppressed down to 36 K. Although we could not fully suppress TC via V substitution, for x=0.16, we performed magnetization measurements under pressure. The ferromagnetic state is suppressed under pressure at an initial rate of dTC/dp≃−11.7 K/GPa and vanishes by 3.3 GPa. The increase of the Rhodes-Wohlfarth ratio suggests that the ferromagnetism in this system evolves toward itinerant as the V concentration increases.