Measurement and Modeling of the Effects of Transcranial Magnetic Stimulation on the Brain
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Ames National Laboratory is a government-owned, contractor-operated national laboratory of the U.S. Department of Energy (DOE), operated by and located on the campus of Iowa State University in Ames, Iowa.
For more than 70 years, the Ames National Laboratory has successfully partnered with Iowa State University, and is unique among the 17 DOE laboratories in that it is physically located on the campus of a major research university. Many of the scientists and administrators at the Laboratory also hold faculty positions at the University and the Laboratory has access to both undergraduate and graduate student talent.
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Abstract
Transcranial Magnetic Stimulation (TMS) is a method of non-invasively modulating the excitability of the brain. TMS relies on the principle of electromagnetic induction in producing an electric field that stimulates neurons. Measuring the effect of TMS in real time and being able to determine its spatiotemporal resolution increase its potential in both research and clinical applications. In this paper, the authors model the electric fields of three TMS coils: Quadruple Butterfly Coil (QBC), Triple Halo Coil (THC) and the Magventure B65 coils, by performing computational finite element (FE) analysis using the Sim4life software. To evaluate the accuracy of the electromagnetic models, we devised a novel experimental protocol that compares the maximum field intensity stimulated using modeling with the induced voltage experimentally measured within a phantom brain in response to TMS.
Comments
This is a manuscript of an article published as Afuwape, Oluwaponmile F., Hiroyuki Oya, Aaron D. Boes, and David C. Jiles. "Measurement and Modeling of the Effects of Transcranial Magnetic Stimulation on the Brain." IEEE Transactions on Magnetics (2020). DOI: 10.1109/TMAG.2020.3008554. Posted with permission.