QSAR Evaluation of Cyanohydrins' Fumigation Toxicity to House Fly (Musca domestica) and Lesser Grain Borer (Rhyzopertha dominica)
Date
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Authors
Research Projects
Organizational Units
The Department of Entomology seeks to teach the study of insects, their life-cycles, and the practicalities in dealing with them, for use in the fields of business, industry, education, and public health. The study of entomology can be applied towards evolution and ecological sciences, and insects’ relationships with other organisms & humans, or towards an agricultural or horticultural focus, focusing more on pest-control and management.
History
The Department of Entomology was founded in 1975 as a result of the division of the Department of Zoology and Entomology.
Related Units
- College of Agriculture and Life Sciences (parent college)
- Department of Zoology and Entomology (predecessor, 1975)
Journal Issue
Is Version Of
Versions
Series
Department
Abstract
Using fumigation toxicity data of 11 natural and synthetic cyanohydrins to house fly (Musca domestica) and a stored-product pest, the lesser grain borer (Rhyzopertha dominica), the quantitative structure−activity relationships (QSAR) of cyanohydrins were examined by Oxford Molecular CAChe 3.2 and Microsoft Excel. This analysis used eight physicochemical parameters. Correlation between the LC50 values for house fly and lesser grain borers was also evaluated. The results showed that log P, polarizability, and molar refractivity are the best descriptors to explain the relationship between the structure of cyanohydrins and biological effects in house flies, and to a lesser degree in lesser grain borers. A significant relationship was also found between the toxicity to house flies and lesser grain borers.
Comments
Reprinted with permission from Journal of Agricultural and Food Chemistry 50 (2002): 5617, doi:10.1021/jf020361t. Copyright 2002 American Chemical Society.