The causes of death in calves at the time of birth or soon thereafter have long been the subject of investigation. Bacterial diseases have received wide-spread attention, and recently nutritional deficiencies have been the object of research. Capable biological chemists have entered this field and are making fine contributions toward the solution of some of the diseases of the new born encountered by the veterinary clinician. In this connection it should be pointed out that the calf loss at the time of parturition and during the succeeding weeks costs the livestock industry a terrific toll. It is said that as high as 20 percent of dairy calves do not reach maturity.