Miscanthus × giganteus is a promising biomass crop for Iowa, based on its high yields and low input requirements. However, several factors are limiting farmer adoption, particularly lack of best management practices (BMPs) that would balance agronomic, economic, and environmental performance. The goal of this project was to establish the “Long-term Assessment of Miscanthus Productivity and Sustainability” (LAMPS) trial at three Iowa sites and develop the human and research infrastructure to identify BMPs for M. × giganteus, with the ultimate goals of furthering Iowa’s bioeconomy and preserving its natural resources.