Mechanisms of Escape from Host Immune Defenses by Apicomplexan Parasites
Date
2020-01-01
Authors
Barlow, Reannan
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Joshua Beck
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Biomedical Sciences
Abstract
A successful pathogen manipulates its host from the moment infection occurs. Apicomplexan parasites are no different. Plasmodium spp., the causative agents of malaria, evade the human immune system so well that they kill hundreds of thousands of people per year. Toxoplasma, though not particularly dangerous to a healthy adult, is a widespread pathogen due to how easily it spreads between host and how it modulates host functions (27). This review discusses how Toxoplasma and Plasmodium avoid clearance by host defenses, highlighting their similarities and differences.
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Wed Jan 01 00:00:00 UTC 2020