Innate Immune Response Induced in Gnotobiotic Piglets by a Mixed Culture of Commensal Bacteria
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The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
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Abstract
Our laboratory has developed a recombined porcine-derived mixed bacterial culture (RPCF) isolated from the ceca of a healthy, pathogen-free pig and have maintained it at steady state in a continuous-flow chemostat. The culture has been shown to protect neonatal and weaned pigs from infection and disease caused by Salmonella and E. coli. However, the mechanism of action of the protection from pathogens observed with the RPCF culture remains unclear.