As a small animal practitioner, seizures are one of the most common neurologic abnormalities encountered. Much of what we know about seizures is derived from the observation and study of human seizure disorders, which have been well recognized since the beginning of recorded history. Once thought to be manifestations of mystical powers or demonic possession, the Greek physician Hippocrates in 400 B.C. theorized that the actual origin of seizures was due to disruptions in the brain itself. Throughout the centuries, seizure disorders have been studied extensively, however, research conducted during the past 80 years on human seizures and epilepsy has greatly increased the understanding of the disorder in animals as well.