This dissertation focuses on the area of supply chain disruption management and aims to make a contribution by studying how firms can manage supply chain disruptions by (i) becoming resilient and by (ii) reducing the risk of supply chain disruption arising out of innovation. Firm resilience is the ability of the firm to: be alert to supply chain disruptions, to adapt and quickly respond to changes brought by a supply chain disruption and the ability to recover and return back to a state of greater competitiveness. In this dissertation, I emphasize the role of firm resilience in mitigating the effects of a supply chain disruption and focus on understanding factors that enhance firm’s resilience. I first develop the concept of firm resilience, explore its antecedents and consequences and empirically establish its nomological and predictive validity. I then look at supply chain disruptions that result from firm’s strategic focus on innovation and consider the role of a risk management infrastructure that a firm has in place in reducing the risk of these disruptions. In this dissertation I use structural equation modeling to as a methodology to test my hypothesis.