The latest generation of smartphones are more powerful than the first computer that sent the man to the moon. These smartphones are increasingly seen as handheld computers due to the capabilities that can be done with smartphones. Therefore, in this thesis, we will demonstrate the utilization of a smartphone-based spectrometer using the CMOS CCD chip of the camera. The characterization and integration between the smartphone and spectrometer is done to ensure robust and reliable results. The smartphone-based spectrometer is able to measure accurately and made to be comparable to industrial spectrometers. This research was done in order to attempt to improve and advance mobile health in this modern age. Many have already profited from the usages of different mobile health technologies and there will be many more in the future. The smartphone-based spectrometer is capable of measuring different biomarkers and observe the change in refractive index and wavelengths. Taking everything into consideration, the spectrometer was made to be compact and hopefully would impact the mobile health technologies in the near future.