A model for the acoustical transfer function of tissue
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The function of the Department of Chemical and Biological Engineering has been to prepare students for the study and application of chemistry in industry. This focus has included preparation for employment in various industries as well as the development, design, and operation of equipment and processes within industry.Through the CBE Department, Iowa State University is nationally recognized for its initiatives in bioinformatics, biomaterials, bioproducts, metabolic/tissue engineering, multiphase computational fluid dynamics, advanced polymeric materials and nanostructured materials.
History
The Department of Chemical Engineering was founded in 1913 under the Department of Physics and Illuminating Engineering. From 1915 to 1931 it was jointly administered by the Divisions of Industrial Science and Engineering, and from 1931 onward it has been under the Division/College of Engineering. In 1928 it merged with Mining Engineering, and from 1973–1979 it merged with Nuclear Engineering. It became Chemical and Biological Engineering in 2005.
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1913 - present
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- Department of Chemical Engineering (1913–1928)
- Department of Chemical and Mining Engineering (1928–1957)
- Department of Chemical Engineering (1957–1973, 1979–2005)
- Department of Chemical and Biological Engineering (2005–present)
- College of Engineering(parent college)
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Abstract
One of the major difficulties in identifying internal tissue structures with current ultrasonic methods if the lack of quantitative and complete retrieval of the acoustical parameters of tissue by a single technique. Therefore, a mathematical model representing the ultrasonic signal modification by a multilayered tissue mass has been developed to quantify the acoustical transfer function of tissue and characterize each tissue layer on the basis of three acoustical parameters;Two reflected signals from the near and far boundaries of each tissue layer were measured and analyzed by Fourier transform methods to obtain the magnitude ratio of the two signals (acoustical transfer function of each tissue layer). Linear regression on the resultant data and simple mathematical computation yield the tissue acoustical parameters: characteristic impedance, propagation, velocity, and amplitude attenuation coefficient;The results indicate that the proposed model is a valid representation of the acoustical transfer function of tissue for normal incidence of the ultrasonic waves since the acoustical parameters predicted by the proposed model agree with those found in the literature.