Students of color regularly face discrimination on college campuses. Ethnic studies courses have been established as a possible method of racial bias reduction in college students. Aversive racism theory and internalized racism research suggest that both explicit and implicit bias should be considered when examining racial bias reduction. Research has also suggested that sex and ethnicity/race may moderate explicit and implicit bias. Results indicate that European American men had the highest explicit racial bias scores, and they were the most likely to have a significant reduction in ethnic studies courses. In general, European American participants had higher scores of implicit racial bias than participants of color. Levels of implicit racial bias did not statistically significantly change for participants across the semester. However, enrollment in a distanced/online ethnic studies course may influence students’ implicit racial bias. Implications for future research concerning racial bias reduction in ethnic studies courses as well as implications for teaching are discussed.