Selective pyrone functionalization: reductive alkylation of triacetic acid lactone

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2015_Kraus_SelectivePyrone.pdf (214.29 KB)
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2014-12-01
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Kraus, George
Basemann, Kevin
Guney, Tezcan
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Kraus, George
University Professor Emeritus
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Chemistry
Abstract

The one-pot reaction of aldehydes, triacetic acid lactone, and Hantzsch 1,4-dihydropyridine affords 3-alkyl pyrones via a reductive alkylation strategy.
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This is a manuscript of an article published as Kraus, George A., Kevin Basemann, and Tezcan Guney. "Selective pyrone functionalization: reductive alkylation of triacetic acid lactone." Tetrahedron Letters 56, no. 23 (2015): 3494-3496. 10.1016/j.tetlet.2015.01.141. Posted with permission.
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http://doi.org/10.1016/j.tetlet.2015.01.141
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https://dr.lib.iastate.edu/handle/20.500.12876/14298
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Chemistry
Keywords
2-Pyrone, Triacetic acid lactone, Reductive alkylation, Aldehydes, Hantzsch ester
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Wed Jan 01 00:00:00 UTC 2014
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