Campus Units

Chemistry, Ames Laboratory

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2-26-2014

Journal or Book Title

Tetrahedron Letters

Volume

55

Issue

9

First Page

1549

Last Page

1551

DOI

10.1016/j.tetlet.2014.01.067

Abstract

Substituted rosamines are efficiently prepared through a new organometallic addition to an imine-substituted xanthone as a novel primary amine equivalent. The synthesis reduces the number of synthetic steps to the targeted rosamines, for convenient and facile access to potential libraries of rosamine dyes. The prepared rosamine derivatives represent unique multifunctional platforms that possess radiolabeling capability and fluorescence. Rosamines have (i) useful non-specific binding properties in mammalian cells and plant root hair, and (ii) positive uptake or binding properties in microbial systems.

Comments

This is a manuscript of an article published as Kraus, George A., Tezcan Guney, Aaron Kempema, Joel M. Hyman, and Bahram Parvin. "Efficient synthesis of fluorescent rosamines: multifunctional platforms for cellular imaging." Tetrahedron Letters 55, no. 9 (2014): 1549-1551. DOI: 10.1016/j.tetlet.2014.01.067. Posted with permission.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Copyright Owner

Elsevier Ltd.

Language

en

File Format

application/pdf

Published Version

Share

COinS