Campus Units

Chemistry, Ames Laboratory

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2016

Journal or Book Title

Physical Chemistry Chemical Physics

Volume

18

Issue

1

First Page

65

Last Page

69

DOI

10.1039/C5CP06505D

Abstract

We study the effects of the deuteration of biradical polarizing agents on the efficiency of dynamic nuclear polarization (DNP) via the cross-effect. To this end, we synthesized a series of bTbK and TOTAPol biradicals with systematically increased deuterium substitution. The deuteration increases the radicals' relaxation time, thus contributing to a higher saturation factor and larger DNP enhancement, and reduces the pool of protons within the so-called spin diffusion barrier. Notably, we report that full or partial deuteration leads to improved DNP enhancement factors in standard samples, but also slows down the build-up of hyperpolarization. Improvements in DNP enhancements factors of up to 70% and time savings of up to 38% are obtained upon full deuteration. It is foreseen that this approach may be applied to other DNP polarizing agents thus enabling further sensitivity improvements.

Comments

This article is published as Perras, Frédéric A., Regina R. Reinig, Igor I. Slowing, Aaron D. Sadow, and Marek Pruski. "Effects of biradical deuteration on the performance of DNP: towards better performing polarizing agents." Physical Chemistry Chemical Physics 18, no. 1 (2016): 65-69. DOI: 10.1039/C5CP06505D. Posted with permission.

Copyright Owner

The Owner Societies

Language

en

File Format

application/pdf

Published Version

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