Fluorescent Nanoparticle Sensors with Tailor-Made Recognition Units and Proximate Fluorescent Reporter Groups
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The Department of Chemistry seeks to provide students with a foundation in the fundamentals and application of chemical theories and processes of the lab. Thus prepared they me pursue careers as teachers, industry supervisors, or research chemists in a variety of domains (governmental, academic, etc).
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The Department of Chemistry was founded in 1880.
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1880-present
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- College of Liberal Arts and Sciences (parent college)
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Abstract
The molecular recognition unit of a fluorescent sensor is its most cumbersome part to design and synthesize, but is key to the specificity of the sensor. Molecular imprinting within cross-linked micelles using easily synthesized modular templates allowed us to create analyte-specific binding sites with a nearby fluorescent probe. This strategy makes it straightforward to vary the recognition unit independent of the reporting unit, making the sensor potentially applicable to a wide range of molecular analytes.
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This is a manuscript of an article published as Xing, Xiaoyu, and Yan Zhao. "Fluorescent nanoparticle sensors with tailor-made recognition units and proximate fluorescent reporter groups." New Journal of Chemistry 42, no. 12 (2018): 9377-9380. DOI: 10.1039/C8NJ01139G. Posted with permission.