Campus Units

Chemistry

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2018

Journal or Book Title

Organic and Biomolecular Chemistry

Volume

16

Issue

16

First Page

2855

Last Page

2859

DOI

10.1039/C8OB00590G

Abstract

Chemical reactions in a confined nanospace can be very different from those in solution. Imine formation between molecular amines and an aldehyde inside a molecularly imprinted receptor was promoted strongly by the binding. Although how well the amine fit in the binding pocket and its electronic nature both influenced the reaction, the freedom of movement for the amine was the most important factor determining the binding-normalized reactivity.

Comments

This is a manuscript of an article published as Xing, Xiaoyu, and Yan Zhao. "Binding-promoted chemical reaction in the nanospace of a binding site: effects of environmental constriction." Organic & Biomolecular Chemistry 16, no. 16 (2018): 2855-2859. DOI: 10.1039/C8OB00590G. Posted with permission.

Copyright Owner

The Royal Society of Chemistry

Language

en

File Format

application/pdf

Published Version

Included in

Chemistry Commons

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