Campus Units

Chemistry, Ames Laboratory

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

11-7-2018

Journal or Book Title

Tetrahedron Letters

Volume

59

Issue

45

First Page

4008

Last Page

4010

DOI

10.1016/j.tetlet.2018.09.058

Abstract

Methyl coumalate readily reacts with enamines at ambient temperature to give lactones, which can be further transformed into isophthalates and tetrahydronaphthoates. Both cyclic and acyclic enamines show good reactivity. Dehydrogenation of tetrahydronaphthoate 4a was achieved on a hundred-gram scale.

Comments

This is a manuscript of an article published as Yu, Huangchao, and George A. Kraus. "Divergent pathways to isophthalates and naphthalate esters from methyl coumalate." Tetrahedron Letters 59, no. 45 (2018): 4008-4010. DOI: 10.1016/j.tetlet.2018.09.058. Posted with permission.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Copyright Owner

Elsevier Ltd.

Language

en

File Format

application/pdf

Published Version

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