Campus Units
Chemistry, Ames Laboratory
Document Type
Article
Publication Version
Accepted Manuscript
Publication Date
11-7-2018
Journal or Book Title
Tetrahedron Letters
Volume
59
Issue
45
First Page
4008
Last Page
4010
DOI
10.1016/j.tetlet.2018.09.058
Abstract
Methyl coumalate readily reacts with enamines at ambient temperature to give lactones, which can be further transformed into isophthalates and tetrahydronaphthoates. Both cyclic and acyclic enamines show good reactivity. Dehydrogenation of tetrahydronaphthoate 4a was achieved on a hundred-gram scale.
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Copyright Owner
Elsevier Ltd.
Copyright Date
2018
Language
en
File Format
application/pdf
Recommended Citation
Yu, Huangchao and Kraus, George A., "Divergent pathways to isophthalates and naphthalate esters from methyl coumalate" (2018). Chemistry Publications. 1269.
https://lib.dr.iastate.edu/chem_pubs/1269
Comments
This is a manuscript of an article published as Yu, Huangchao, and George A. Kraus. "Divergent pathways to isophthalates and naphthalate esters from methyl coumalate." Tetrahedron Letters 59, no. 45 (2018): 4008-4010. DOI: 10.1016/j.tetlet.2018.09.058. Posted with permission.