Campus Units
Chemistry
Document Type
Article
Publication Version
Published Version
Publication Date
2020
Journal or Book Title
Organic & Biomolecular Chemistry
Volume
18
Issue
3
First Page
495
Last Page
499
DOI
10.1039/C9OB02486G
Abstract
A robust lipophilic dye, based on the structures of the benzothiadiazole heterocycle, was shown to be a potent fluorescent stain for the selective imaging of lipid droplets (LDs) within both live and fixed human cells. Its small molecular framework, large Stokes shift, and vastly improved photostability over that of the current status quo, Nile Red, highlight its tremendous potential as a versatile chemical tool for facilitating LD imaging and research.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License
Copyright Owner
The Royal Society of Chemistry
Copyright Date
2020
Language
en
File Format
application/pdf
Recommended Citation
Suarez, S. Israel; Warner, Caroline C.; Brown-Harding, Heather; Thooft, Andrea M.; VanVeller, Brett; and Lukesh, John C. III, "Highly selective staining and quantification of intracellular lipid droplets with a compact push–pull fluorophore based on benzothiadiazole" (2020). Chemistry Publications. 1276.
https://lib.dr.iastate.edu/chem_pubs/1276
Comments
This article is published as Suarez, S. Israel, Caroline C. Warner, Heather Brown-Harding, Andrea M. Thooft, Brett VanVeller, and John C. Lukesh. "Highly selective staining and quantification of intracellular lipid droplets with a compact push–pull fluorophore based on benzothiadiazole." Organic & Biomolecular Chemistry 18, no. 3 (2020): 495-499. DOI: 10.1039/C9OB02486G. Posted with permission.