Campus Units

Chemistry

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2018

Journal or Book Title

Supramolecular Chemistry

Volume

30

Issue

11

First Page

929

Last Page

939

DOI

10.1080/10610278.2018.1489540

Abstract

Molecular recognition in water is challenging but water-soluble molecularly imprinted nanoparticle (MINP) receptors were produced readily by double cross-linking of surfactant micelles in the presence of suitable template molecules. When the micellar surface was decorated with different polyhydroxylated ligands, significant interactions could be introduced between the surface ligands and the template. Flexible surface ligands worked better than rigid ones to interact with the polar moiety of the template, especially for those template molecules whose water-exposed surface is not properly solvated by water. The importance of these hydrophilic interactions was examined in the context of different substrates, density of the surface ligands, and surface-cross-linking density of the MINP. Together with the hydrophobic interactions in the core, the surface hydrophilic interactions can be used to enhance the binding of guest molecules in water.

Comments

This is an Accepted Manuscript of an article published by Taylor & Francis in Supramolecular Chemistry on July 20, 2018, available online at DOI: 10.1080/10610278.2018.1489540. Posted with permission.

Copyright Owner

Taylor & Francis Group, LLC

Language

en

File Format

application/pdf

Published Version

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