Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

11-2007

Journal or Book Title

Organic Letters

Volume

9

Issue

25

First Page

5147

Last Page

5150

DOI

10.1021/ol701883u

Abstract

A molecular basket with four cholate units assembled on a cone-shaped calix[4]arene assumed reversed micelle-like conformation in 5% methanol/carbon tetrachloride. The inwardly facing hydroxyl groups on the cholates concentrated the polar solvent from the mostly nonpolar mixture. Methanolysis of alkyl halides benefited from the concentrated pocket of methanol if the substrate was capable of entering the basket. Substrates that were too large or too hydrophobic to fit within the basket showed no rate acceleration.

Comments

Reprinted (adapted) with permission from Organic Letters 9 (2007): 5147, doi:10.1021/ol701883u. Copyright 2007 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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