Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

8-2004

Journal or Book Title

Organic Letters

Volume

6

Issue

18

First Page

3187

Last Page

3189

DOI

10.1021/ol048679p

Abstract

When four facially amphiphilic cholate derivatives are attached to a tetraaminocalixarene scaffold, the resulting molecule responds to environmental changes by rotation of the cholate units. In polar solvents, the molecule adopts a micellelike conformation with the hydrophilic α-faces of the cholates pointing outward. In nonpolar solvents, it turns inside out, assuming a reversed micellelike conformation with the hydrophobic β-faces pointing outward. Switching between the two conformations is driven by solvophobic interactions and is fully reversible.

Comments

Reprinted (adapted) with permission from Organic Letters (2004): 3187, doi:10.1021/ol048679p. Copyright 2004 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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