Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

5-2005

Journal or Book Title

Langmuir

Volume

21

Issue

14

First Page

6235

Last Page

6239

DOI

10.1021/la050621b

Abstract

A cholate derivative with three epoxide groups was synthesized from cholic acid by allylation followed by epoxidation. Ring opening of the epoxides by various nucleophiles yielded facial amphiphiles with anionic, cationic, or nonionic functional groups. The critical micelle concentrations of these amphiphiles largely depend on the number of charged groups on the molecule. A facial amphiphile with pH-tunable micellization was prepared. Its aggregation behavior changes abruptly at pH = 7.6−6.6 as a result of protonation of its amino groups.

Comments

Reprinted (adapted) with permission from Langmuir (2005): 6235, doi:10.1021/la050621b. Copyright 2005 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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