Journal or Book Title
Benign by Design: Alternative Synthetic Design for Pollution Prevention
The Friedel-Crafts reaction, a widely used reaction in both industrial and academic laboratories, produces several byproducts which must be handled as pollutants. An alternative which involves the photochemically-mediated reaction of an aldehyde with a quinone is described. This alternative chemistry can be applied to direct syntheses of the ring systems of the benzodiazepines and benzoxepins.
Kraus, G.A., et al.
Kraus, George A.; Kirihara, Masayuki; and Wu, Yusheng, "A photochemical Alternative to the Friedel--Crafts Reaction" (1994). Chemistry Publications. 282.