Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

6-15-2009

Journal or Book Title

The Journal of Organic Chemistry

Volume

74

Issue

15

First Page

5337

Last Page

5341

DOI

10.1021/jo900718g

Abstract

The reaction of substituted (2-aminobenzyl)triphenylphosphonium bromides with aromatic aldehydes or α,β-unsaturated aldehydes constitutes a new synthesis of 2,3-disubstitued indoles in high yields. The adduct from 4-oxo-3,4-dihydroquinazoline-2-carbaldehyde was an advanced intermediate in the synthesis of several rutaecarpines.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 74(15); 5337-5341. Doi: 10.1021/jo900718g. Copyright 2009 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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