Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

9-1991

Journal or Book Title

The Journal of Organic Chemistry

Volume

56

Issue

19

First Page

5688

Last Page

5691

DOI

10.1021/jo00019a042

Abstract

Aflatoxin analogue 19 was prepared by a direct sequence involving a novel silver-mediated cyclization to 12, the Michael addition of 16 with 17, and the oxidation of the Michael addition adduct. The overall yield of this six-step route is approximately 11%. The pathway is a flexible one that will permit the synthesis of analogues for toxicological analysis.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 56(19); 5688-5691. Doi: 10.1021/jo00019a042. Copyright 1991 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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