Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

10-1982

Journal or Book Title

The Journal of Organic Chemistry

Volume

47

Issue

22

First Page

4337

Last Page

4340

DOI

10.1021/jo00143a034

Abstract

The preparation of a tetradeoxy anthracyclinone is described. The key reaction is the cyclization of the acetylenic coumarin 10 to anthraquinone 11. Interestingly, the related model system 12 failed to cyclize. The transformation of 11 into the desired compound 13 was effected by straightforward reactions. The key intramolecular cyclization reaction is also useful for the preparation of phthalide quinone 7.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 47(22); 4337-4340. Doi: 10.1021/jo00143a034. Copyright 1982 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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