A direct synthesis of .beta.-hydroxybutyrolactones. Total synthesis of dendrolasin and formal total synthesis of aplysistatin

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1983-12-01
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Kraus, George
Gottschalk, Peter
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Kraus, George
University Professor Emeritus
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Chemistry
Abstract

The 6-hydroxybutyrolactone unit has been employed as a building block for the synthesis of several furans and sesquiterpenes. Negishi and co-workers' developed a clever route to dendrolasin (1).

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Reprinted (adapted)with permission from The Journal of Organic Chemistry, 48(26); 5356-5357. Doi: 10.1021/jo00174a038. Copyright 1983 American Chemical Society.

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Sat Jan 01 00:00:00 UTC 1983
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