Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

9-1985

Journal or Book Title

The Journal of Organic Chemistry

Volume

50

Issue

18

First Page

3252

Last Page

3255

DOI

10.1021/jo00218a002

Abstract

An extremely direct route to the 6-deoxyanthracycline skeleton is described. The initial route to quinone 10 failed due to an unexpected complication in the Ago demethylation step. However, starting from 2-bromo- 1,4-dimethoxynaphthalene, furan 17 could be prepared in two steps. Furan 17 was then converted into anthraquinone 19 in five steps. The eight-step route proceeds in 9% overall yield.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 50(18); 3252-3255. Doi: 10.1021/jo00218a002. Copyright 1985 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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