Journal or Book Title
Catalytic systems derived from [Os(TTP)]2 or Fe(TTP) (TTP = 5,10,15,20-tetra-p-tolylporphyrinato) are extremely efficient at converting styrenes and diazo reagents to cyclopropanes in high yields and high stereoselectivity. A number of mechanistic studies have been undertaken to elucidate the catalytic pathway. A mono(carbene) complex, (TTP)OsCHCO2Et, has been isolated but is not the catalytically active species. An electron-withdrawing ligand trans to the carbene in (TTP)OsCHCO2Et activates the carbon fragment toward transfer to an olefin. Labeling studies with (TTP)OsCHX and N2CHY and substrate reactivity profiles are consistent with a trans-osmium(II) bis(carbene) species as the active catalyst.
American Chemical Society
Hamaker, Christopher G.; Djukic, Jean-Pierre; Smith, Daniel A.; and Woo, L. Keith, "Mechanism of Cyclopropanation Reactions Mediated by (5,10,15,20-Tetra-p-tolylporphyrinato)osmium(II) Complexes" (2001). Chemistry Publications. 757.