Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

5-1981

Journal or Book Title

The Journal of Organic Chemistry

Volume

46

Issue

11

First Page

2417

Last Page

2419

DOI

10.1021/jo00324a050

Abstract

Although tetrahydrofurans and tetrahydropyrans are important structural subunits of many classes of natural products,l comparatively few general synthetic methods are known? Since y- and &lactones are readily available: an efficient and versatile transformation to the ether would significantly extend current methodology. The conversion of a lactone to an ether has been accomplished by hydride reduction to a diol followed by cyclization by way of a monotosylate4 or other activated ester.5

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 46(11); 2414-2419. Doi: 10.1021/jo00324a050. Copyright 1981 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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