Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

11-1981

Journal or Book Title

The Journal of Organic Chemistry

Volume

46

Issue

23

First Page

4791

Last Page

4792

DOI

10.1021/jo00336a036

Abstract

In conjunction with our studies of the amidoalkylation reaction,' multigram quantities of N-acyl-2-pyrrolines (1) were needed. Interestingly, only a few methods for the synthesis of this class of compounds had been reported. Stille and co-workers prepared 1 by a novel transition metal mediated isomerization of N-acyl-3-pyrrolines2 and also cyclized (acy1amino)butyraldehydes to produce le3 Although these methods are excellent for qmall-scale preparation, large-scale reactions would entail considerable expense.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry,46(23); 4791-4792. Doi: 10.1021/jo00336a036. Copyright 1981 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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