Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

2-1982

Journal or Book Title

Journal of The American Chemical Society

Volume

104

Issue

4

First Page

1114

Last Page

1116

DOI

10.1021/ja00368a043

Abstract

Several macrocyclic lactones of the trichothecene class of compounds exhibit significant anticancer activity.' A common structural subunit in each of these lactones is the sesquiterpene verrucarol(1). Anguidin (2), a more highly oxygenated analogue, also shows inhibitory activity against several cancers., Calonectrin (3), considered to be the biogenetic precursor to verru~arol,~ has recently been isolated.

Comments

Reprinted (adapted) with permission from Journal of the American Chemical Society,104(4); 1114-1116. Doi: 10.1021/ja00368a043. Copyright 1982 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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