Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

7-1979

Journal or Book Title

The Journal of Organic Chemistry

Volume

44

Issue

14

First Page

2480

Last Page

2482

DOI

10.1021/jo01328a031

Abstract

A general procedure is described where an aryllithium, generated by metalation of a protected phenol with n-butyllithium, adds in a conjugate manner to diethyl ethoxymethylenemalonate to give after acid hydrolysis an oxygenated 3-carbethoxycoumarin. By this procedure the ethyl vinyl ethers 9, 11, 13, and 15 are converted into the corresponding coumarins 10, 12, 14, and 16 in a single reaction vessel in good yield.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 44(14); 2480-2482. Doi: 10.1021/jo01328a031. Copyright 1979 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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