Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

4-1993

Journal or Book Title

Journal of the American Chemical Society

Volume

115

Issue

8

First Page

3384

Last Page

3385

DOI

10.1021/ja00061a069

Abstract

Hypericin (Figure 1) has been shown by Lavieet al. toinactivate mature and properly assembled retroviruses, notably human immunodeficiency virus (HIV).' Recently Kraus, Carpenter, and co-workers demonstrated the antiretroviral activity of hypericin against equine infectious anemia virus (EIAV), a lentivirus closely related to HIV, and have determined that light is required for activity.2 The requirement of light leads to the fundamental questions, what is the mechanism of action of hypericin and what is the role of light?

Comments

Reprinted (adapted) with permission from Journal of the American Chemical Society 115 (1993): 3384, doi: 10.1021/ja00061a069. Copyright 1993 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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