Campus Units

Chemistry

Document Type

Article

Publication Version

Published Version

Publication Date

1-2004

Journal or Book Title

Journal of Chemical Physics

Volume

120

Issue

4

First Page

2005

Last Page

2009

DOI

10.1063/1.1634955

Abstract

In this report we present a general formulation to calculate the van der Waals interaction between two protein molecules in an electrolyte solution using boundary element method of solving linearized Poisson–Boltzmann equation. Our formulation is based upon an inhomogeneous dielectric model of proteins at the residue level. Our results for bovine pancreatic trypsin inhibitor at various relative orientations indicate that the anisotropy of the interaction can be tens of kBT.

Comments

The following article appeared in Journal of Chemical Physics 120 (2004): 2005, and may be found at doi:10.1063/1.1634955.

Rights

Copyright 2004 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

Copyright Owner

American Institute of Physics

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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