BODIPY-Derived Photoremovable Protecting Groups Unmasked with Green Light
Reprinted (adapted) with permission from Journal of the American Chemical Society, 137(11); 3783-3786. Doi: 10.1021/jacs.5b01297. Copyright 2015 American Chemical Society.
Photoremovable protecting groups derived from meso-substituted BODIPY dyes release acetic acid with green wavelengths >500 nm. Photorelease is demonstrated in cultured S2 cells. The photocaging structures were identified by our previously proposed strategy of computationally searching for carbocations with low-energy diradical states as a possible indicator of a nearby productive conical intersection. The superior optical properties of these photocages make them promising alternatives