Porcine Reproductive and Respiratory Syndrome virus (PRRSV) is a highly mutagenic pathogen affecting the global modern swine population. At the herd level, controlling and eliminating the virus is still challenging in part due its ever-expanding genetic diversity, and the fact that it establishes a prolonged infection. At the regional level, PRRSV control requires the cooperation of neighboring producers and veterinarians dedicated to stopping area spread, which can occur through personnel, equipment, vehicles, and airborne.

The initial voluntary PRRSV regional control programs were focused on routine diagnostic testing for PRRSV and voluntary data-sharing regarding virus circulation in participants' herds, however, no pre-defined action plans or decision trees have been utilized in PRRS regional programs in the US.

In this creative component we propose the coordinated implementation of the newest tools and strategies for monitoring wild-type PRRS in the swine industry, the monitoring of productivity data to support diagnostic testing, automated diagnostic access and communication, and an upon-agreed action plan describing different interventions that should be implemented by the project participants.

The monitoring protocol is linked to a regional and site-specific PRRSV status classification, which is used as the foundation for the interventions described in the action plan, which is flexible according to the prevalence of wild-type PRRSV in the region. The simultaneous implementation of the aforementioned strategies allows early detection of a potential wild-type PRRSV virus introduction, as well the early intervention, which will be guided by the upon-agreed action plan.