The Middle East region is of great importance in the accounts of many countries in the world, and the United States of America comes to the forefront. Although the American strategy in that region had been based on a set of constants represented by the attempt to control fluctuation around the oil industry, preserving the security of Israel, and protecting other American interests, the post-9/11 world has produced a new set of goals for us in the region (fighting extremism, spread democracy etc.), but most importantly, a change in the means to achieving these goals. Indeed, the United States relies much more on the direct use of military force to protect and preserve those interests now. In this research, we examine the American diplomacy in the Middle East and its results in the post-9/11 period, with a focus on the strategy and outcomes in Iraq and the Arab spring for Egypt. In fact, the paper came to briefly address this change of policy through a number of axes.