Campus Units
Computer Science
Document Type
Article
Publication Version
Published Version
Publication Date
5-8-2008
Journal or Book Title
Nature
Volume
453
Issue
7192
First Page
175
Last Page
183
DOI
10.1038/nature06936
Abstract
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology. Expansions of protein, non-protein-coding RNA and microRNA families, as well as repeat elements, are identified. Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.
Copyright Owner
Nature Publishing Group
Copyright Date
2008
Language
en
File Format
application/pdf
Recommended Citation
Warren, Wesley C.; Huang, Xiaoqiu; and et al., "Genome analysis of the platypus reveals unique signatures of evolution" (2008). Computer Science Publications. 24.
https://lib.dr.iastate.edu/cs_pubs/24
Included in
Animal Sciences Commons, Evolution Commons, Genetics and Genomics Commons, Population Biology Commons
Comments
This article is published as Warren, Wesley C., LaDeana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov et al. "Genome analysis of the platypus reveals unique signatures of evolution." Nature 453, no. 7192 (2008): 175. doi: 10.1038/nature06936.