Campus Units

Ecology, Evolution and Organismal Biology

Document Type

Article

Publication Version

Accepted Manuscript

Publication Date

2020

Journal or Book Title

National Science Review

DOI

10.1093/nsr/nwaa277

Abstract

Allopolyploidy is an important process in plant speciation, yet newly formed allopolyploid species typically suffer from extreme genetic bottlenecks. One escape from this impasse might be homoeologous meiotic pairing, during which homoeologous exchanges (HEs) generate phenotypically variable progeny. However, the immediate genome-wide patterns and resulting phenotypic diversity generated by HEs remain largely unknown. Here, we analyzed the genome composition of 202 phenotyped euploid segmental allopolyploid individuals from the 4th selfed generation following chromosomal doubling of reciprocal F1 hybrids of crosses between rice subspecies, using whole genome sequencing. We describe rampant occurrence of HEs that, by overcoming incompatibility or conferring superiority of hetero-cytonuclear interactions, generate extensive and individualized genomic mosaicism across the analyzed tetraploids. We show that the resulting homoeolog copy number alteration in tetraploids affects known-function genes and their complex genetic interactions, in the process creating extraordinary phenotypic diversity at the population level following a single initial hybridization. Our results illuminate the immediate genomic landscapes possible in a tetraploid genomic environment, and underscore HE as an important mechanism that fuels rapid phenotypic diversification accompanying the initial stages of allopolyploid evolution.

Comments

This is a manuscript of an article published as Wu, Y., Lin, F., Zhou, Y., Wang, J., Sun, S., Wang, B., Zhang, Z., Li, G., Lin, X., Wang, X. and Sun, Y., 2020. Genomic mosaicism due to homoeologous exchange generates extensive phenotypic diversity in nascent allopolyploids. National Science Review (2020). doi: 10.1093/nsr/nwaa277.

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Copyright Owner

The Authors

Language

en

File Format

application/pdf

Published Version

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