Campus Units
Entomology
Document Type
Article
Publication Version
Published Version
Publication Date
2003
Journal or Book Title
Journal of Agricultural and Food Chemistry
Volume
51
Issue
26
First Page
7725
Last Page
7729
DOI
10.1021/jf030492+
Abstract
A steady-state bioconcentration and elimination of sulfamethazine (SM2) in the sturgeon (A. schrenkii) was conducted in flow-through aqueous conditions. Two treated groups of fish were exposed to concentrations of 1.00 and 0.10 mg/L of SM2, respectively. SM2 and its main metabolite, N4-acetyl-SM2, were determined in both fish muscle and water during the 8-day uptake period and the subsequent 6-day elimination period. Rapid uptakes of the drug were observed in both treated groups. Muscle tissue residues plateaued after ∼3 days. The bioconcentration factor in muscle (BCFm) in the low-concentration drug solution was 1.19 and that in the high-concentration-treated level was 0.61. The calculated biodegradation index was 3.72%. The elimination half-times (t1/2) of the two treatment levels were 19.44 and 23.52 h, respectively. The result indicates that SM2 will neither bioconcentrate in individual aquatic organisms nor biomagnify in the food chain, although the BCFm was relatively higher under the low-concentration exposure.
Copyright Owner
American Chemical Society
Copyright Date
2003
Language
en
File Format
application/pdf
Recommended Citation
Hou, Xiaolin; Shen, Jianzhong; Zhang, Suxia; Jiang, Haiyang; and Coats, Joel R., "Bioconcentration and Elimination of Sulfamethazine and Its Main Metabolite in Sturgeon (Acipenser schrenkii)" (2003). Entomology Publications. 314.
https://lib.dr.iastate.edu/ent_pubs/314
Comments
Reprinted with permission from Journal of Agricultural and Food Chemistry 51 (2003): 7725, doi:10.1021/jf030492+. Copyright 2003 American Chemical Society.