Campus Units

Entomology

Document Type

Article

Publication Version

Published Version

Publication Date

2003

Journal or Book Title

Journal of Agricultural and Food Chemistry

Volume

51

Issue

26

First Page

7725

Last Page

7729

DOI

10.1021/jf030492+

Abstract

A steady-state bioconcentration and elimination of sulfamethazine (SM2) in the sturgeon (A. schrenkii) was conducted in flow-through aqueous conditions. Two treated groups of fish were exposed to concentrations of 1.00 and 0.10 mg/L of SM2, respectively. SM2 and its main metabolite, N4-acetyl-SM2, were determined in both fish muscle and water during the 8-day uptake period and the subsequent 6-day elimination period. Rapid uptakes of the drug were observed in both treated groups. Muscle tissue residues plateaued after ∼3 days. The bioconcentration factor in muscle (BCFm) in the low-concentration drug solution was 1.19 and that in the high-concentration-treated level was 0.61. The calculated biodegradation index was 3.72%. The elimination half-times (t1/2) of the two treatment levels were 19.44 and 23.52 h, respectively. The result indicates that SM2 will neither bioconcentrate in individual aquatic organisms nor biomagnify in the food chain, although the BCFm was relatively higher under the low-concentration exposure.

Comments

Reprinted with permission from Journal of Agricultural and Food Chemistry 51 (2003): 7725, doi:10.1021/jf030492+. Copyright 2003 American Chemical Society.

Copyright Owner

American Chemical Society

Language

en

File Format

application/pdf

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