Journal or Book Title
Pesticide Transformation Products
Pesticides are degraded by many different mechanisms. Physical, chemical, and biological agents play significant roles in the transformation of insecticide, herbicide, and fungicide molecules to various degradation products. Transformation mechanisms include oxidation, hydrolysis, reduction, hydration, conjugation, isomerization, and cyclization. Resultant products are usually less bioactive than the parent psticide molecule, but numerous cases have been documented of metabolites with greater bioactivity. The physical and chemical properties of the degradation products are also different from those of the parent compound, and their fate and significance in the environment also are altered with the structural changes. The concept of "environmental activation" is introduced, to describe the transformation of a pesticide to a degradation product that is of significance in the environment as a result of its environmental toxicology or chemistry.
American Chemical Society
Coats, Joel R., "Pesticide Degradation Mechanisms and Environmental Activation" (1991). Entomology Publications. 379.