Biomedical Sciences, Entomology
Journal or Book Title
Biopesticides: State of the Art and Future Opportunities
ACS Symposium Series, Vol. 1172
Plants have evolved beneficial and protective mechanisms including the production of essential oils. Essential oils are the odiferous component of plant extracts, which give plants a variety of unique properties. Essential oils are composed of various terpenoid compounds, particularly monoterpenoids and related aromatic compounds, along with sesquiterpenoids. A variety of terpenoids have been shown to have a toxic effect against insects. It is thought that this toxic action occurs through a neurological mechanism of action. Octopamine receptors and tyramine receptors are G-Protein-Coupled Receptors (GPCRs) primarily found in invertebrates, including insects. GPCRs have been a popular target for pharmaceutical development but not for agrochemical development. A summary of insect octopaminergic and tyraminergic systems is discussed.
American Chemical Society
Gross, Aaron D.; Kimber, Michael J.; and Coats, Joel R., "G-Protein-Coupled Receptors (GPCRs) as Biopesticide Targets: A Focus on Octopamine and Tyramine Receptors" (2014). Entomology Publications. 397.