Degree Type

Dissertation

Date of Award

2009

Degree Name

Doctor of Philosophy

Department

Chemistry

First Advisor

Daniel W. Armstrong

Second Advisor

Victor S. Lin

Abstract

This thesis shows the systematic variation of both the cation and anion to find an ionic liquid matrix that produces the greatest analyte S/N ratio. It is also demonstrated that these new ILMs have a greater mass detection range and can be used for a wider variety of analytes. Analytes tested include peptides, proteins, and carbohydrates.

Also reported is the characterization of sixteen biodegradable polymers with two ILMs and five solid matrices. It is shown that the ILM produces less degradation and typically allows detection of an almost Gaussian distribution of analyte peaks. This allows detection of a more accurate and precise number average molecular weight and weight average molecular weight.

It is also shown that the use of an ionic liquid stationary phase as the secondary column, in 2D-GC, for the separation of volatile organic compounds and 13 chemical markers found in the headspace of US currency. Tthe use of 2D-GC in the stop flow operation mode is also shown.

It is also shows the separation of phosphorus-oxygen (P-O) containing compounds from a complex mixture using a triflate ionic liquid column as the secondary column in 2D-GC. These phosphorus-oxygen containing compounds are chemical warfare agent simulants. The separation of the P-O containing compounds on the triflate ionic liquid and the commercial DB-WAX (polyethylene glycol) columns are compared. It was found that the triflate IL column was much more selective for the P-O containing compounds than was the DB-WAX column.

Copyright Owner

Jeffrey Aaron Crank

Language

en

Date Available

2012-04-29

File Format

application/pdf

File Size

182 pages

Included in

Chemistry Commons

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