During the early nineteenth-century, a number of authors sought to revise the traditional story of Cain, frequently using non-canonical sources to complete these revisions. The plethora of texts which work to revise this biblical tradition in Romantic Literature certainly makes the modern day reader wonder what caused this apparently widespread impulse. This issue becomes especially curious when considering the diverse authors who undertook the task of revising the story of Cain. In this critical analysis, I examine three different revisions of Cain by authors George Gordon, Lord Byron, Samuel Taylor Coleridge, and Percy Bysshe Shelley to understand what makes the story of Cain so enticing to these authors, and how Cain might hold themes that the authors use to understand the intersections of religion and science in contemporary England.