Date of Award
Doctor of Philosophy
Richard C. Larock
Using readily available substrates, a variety of medicinally and biologically important molecules can now be easily prepared by a one-pot transformation involving a reaction with aryne intermediates. The highly reactive arynes have been generated from commercially available or readily prepared o-(trimethylsilyl)aryl triflates and a fluoride source under relatively mild conditions.
Anton Vladimirovich Dubrovskiy
Dubrovskiy, Anton Vladimirovich, "Novel aryne-mediated synthetic methodologies" (2012). Graduate Theses and Dissertations. 12656.